The concept of desire is seen in all philosophies, religions, and groups of people. However, how these groups go about their desires widely differs. Some groups believe that fulfilling desires should come within oneself, while others believe that praying and asking for help is a better solution. The relationship between these two theories is untouched in literature; most pieces feature one view or the other. In my paper, I delve into the centuries-long conflict between the two. Stoicism- a theoretical, philosophical, and academic movement- calls for the internal motivation for desires and does not believe people should desire what is out of their reach. This is examined more closely in the essay through Epictetus’ The Handbook. Contrarily, Christianity allows people to desire what is out of their control, which is often why Christians talk to their God. This method of desire is displayed in the Anima Christi, which is unraveled in the essay as well. Personally, I think both groups of people have a slightly wrong idea of desire. Rather than choosing one, I think that the combination of the two would be the most sufficient way to reach self-cultivation. With the Stoic idea that one should have personal motivation, and the Christian idea of praying and relying on others, I believe that one can achieve his desires.